Modern understanding of bronchial asthma with fixed airflow obstruction
نویسندگان
چکیده
منابع مشابه
Asthma and irreversible airflow obstruction.
To determine whether asthma alone can cause irreversible airflow obstruction 42 men and 47 women with chronic asthma (mean duration 22 (SD 13) years) without evidence of other disease likely to cause irreversible airflow obstruction were treated with theophylline orally and a beta agonist both orally and by inhalation for four weeks. After two weeks of treatment the FEV1 was less than 85% of th...
متن کاملWhat defines airflow obstruction in asthma?
Asthma guidelines from the Global Initiative for Asthma (GINA) and from the National Heart, Lung, and Blood Institute provide conflicting definitions of airflow obstruction, suggesting a fixed forced expiratory volume in 1 s (FEV(1))/forced vital capacity (FVC) cut-off point and the lower limit of normality (LLN), respectively. The LLN was recommended by the recent American Thoracic Society/Eur...
متن کاملSmoking, asthma, chronic airflow obstruction and COPD.
Cigarette smoking is the most prevalent risk factor for the development of adult-onset respiratory diseases associated with airflow obstruction, namely emphysema and chronic bronchitis, commonly called chronic obstructive pulmonary disease (COPD). Regrettably, childhood asthma does not reduce the likelihood of initiation of smoking [1] but it is not fully clear how smoking impacts pre-existing ...
متن کاملFixed airflow obstruction in asthma: a descriptive study of patient profiles and effect on treatment responses
BACKGROUND The role of fixed airflow obstruction (FAO) in asthma is unclear. OBJECTIVE To assess the relationship between FAO and clinical features of asthma and the effect of FAO on treatment response. METHODS Post hoc descriptive analysis of data stratified by FAO category (screening post-albuterol FEV1/FVC <lower limit of normal [LLN] [FAO+] or ≥LLN [FAO-]) from two 12-week, randomized, ...
متن کاملParameters associated with persistent airflow obstruction in chronic severe asthma.
The significance of severe airflow obstruction in severe asthma is unclear. The current study determined whether severe airflow obstruction is related to inflammatory or structural changes in the airways. Patients with severe asthma from a tertiary referral clinic were divided into two groups according to their postbronchodilator forced expiratory volume in one second (FEV1): severe persistent ...
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ژورنال
عنوان ژورنال: Terapevticheskii arkhiv
سال: 2021
ISSN: 2309-5342,0040-3660
DOI: 10.26442/00403660.2021.03.200661